Skip to content

RAD-140: A Promising Contender for Testosterone Replacement Therapy


Introduction to RAD-140

Testosterone replacement therapy (TRT) has been a widely accepted treatment for hypogonadism and other conditions related to testosterone deficiency. However, the search for safer and more effective alternatives has led to the emergence of selective androgen receptor modulators (SARMs). One such SARM, RAD-140 (Testolone), has been gaining attention for its potential to provide a suitable alternative to traditional testosterone replacement therapy. In this article, we will explore the mechanisms of RAD-140, its benefits, and its potential as a safer and more convenient option for individuals seeking hormone optimisation.

Understanding RAD-140 and its Mechanisms

RAD-140 is a non-steroidal selective androgen receptor modulator developed by Radius Health, Inc. Its primary objective is to target androgen receptors in the body, much like testosterone. However, unlike exogenous testosterone, RAD-140 is more tissue-selective, meaning it tends to act predominantly on muscles and bones, while sparing other tissues such as the prostate. This characteristic holds the promise of reducing unwanted side effects associated with traditional TRT, such as prostate enlargement and cardiovascular risks.

Furthermore, RAD-140 does not undergo aromatisation, the process by which testosterone converts to estrogen, which is another reason it may be considered a safer alternative. Aromatisation can lead to estrogen-related side effects like gynecomastia, water retention, and mood swings. By avoiding this process, RAD-140 may offer a more streamlined hormonal experience.

Benefits of RAD-140

  1. Muscle Mass and Strength: One of the primary reasons athletes and bodybuilders are interested in RAD-140 is its potential to increase muscle mass and strength. Research suggests that RAD-140 can enhance protein synthesis and boost nitrogen retention in muscle tissues, leading to improved muscle growth and recovery.
  2. Bone Health: Maintaining strong bones is crucial, especially as individuals age. Studies have shown that RAD-140 has a positive impact on bone health by increasing bone mineral density, potentially reducing the risk of fractures and osteoporosis.
  3. Fat Loss: RAD-140 may also aid in fat loss due to its impact on metabolism and muscle mass. As lean muscle increases, so does the body’s ability to burn calories, leading to a potential reduction in body fat percentage.
  4. Endurance and Stamina: Users have reported increased endurance and stamina while using RAD-140, which can be beneficial for athletes and individuals engaged in regular physical activity.
  5. Neuroprotective Effects: Some studies suggest that RAD-140 may have neuroprotective properties, potentially benefiting brain health and cognitive function. This aspect sets RAD-140 apart from traditional TRT and highlights its broader range of potential applications.

Safety Profile of RAD-140

While all this seems promising, it is essential to acknowledge that the long-term safety of SARMs is still relatively unexplored. Clinical trials have primarily focused on short-term usage and generally involved healthy individuals rather than those with specific medical conditions. As such, potential risks and side effects of prolonged use are not yet fully understood.

Some of the reported side effects include mild testosterone suppression, which might be less pronounced compared to traditional anabolic steroids but still warrants caution. Post-cycle therapy (PCT) may be necessary to restore natural testosterone production after use, especially for those who use it for extended periods or in higher doses.


RAD-140 shows considerable potential as a suitable alternative to testosterone replacement therapy for individuals seeking hormone optimisation. Its selective targeting of androgen receptors, combined with its potential for increased muscle mass, bone health, and fat loss, makes it an attractive option. However, it is crucial to emphasise that more research is needed to fully understand its long-term safety and efficacy compared to traditional TRT.

If you are considering this alternative, it is essential to consult with a qualified healthcare professional who can assess your individual needs and guide you through the potential risks and benefits. As with any supplement or medication, responsible use and informed decision-making are paramount to prioritise your health and well-being.

RAD 140 (Testolone) – 60 x 10mg Capsules | UK (

Share This Post

Our Product Categories

Recommended Posts

No comment yet, add your voice below!

Add a Comment

Your email address will not be published. Required fields are marked *